Real-World AI Experiences

Clinical studies showing that AI helps radiologists interpret medical images are great, but how well does AI work in the real world – and what do radiologists think about it? These questions are addressed in a new study in Applied Ergonomics that takes a deep dive into the real-world implementation of a commercially available AI algorithm at a German hospital. 

A slew of clinical studies supporting AI were published in 2023, from the MASAI study on AI for breast screening to smaller studies on applications like opportunistic screening or predicting who should get lung cancer screening

  • But even an AI algorithm with the best clinical evidence behind it could fall flat if it’s difficult to use and doesn’t integrate well with existing radiology workflow.

To gain insight into this issue, the new study tracked University Hospital Bonn’s implementation of Quantib’s Prostate software for interpreting and documenting prostate MRI scans (Quantib was acquired by RadNet in January 2022). 

  • Researchers described the solution as providing partial automation of prostate MRI workflow, such as helping segment the prostate, generating heat maps of areas of interest, and automatically producing patient reports based on lesions it identifies. 

Prostate was installed at the hospital in the spring of 2022, with nine radiology residents and three attending physicians interviewed before and after implementation, finding…

  • All but one radiologist had a positive attitude toward AI before implementation and one was undecided 
  • After implementation, seven said their attitudes were unchanged, one was disappointed, and one saw their opinion shift positively
  • Use of the AI was inconsistent, with radiologists adopting different workflows and some using it all the time with others only using it occasionally
  • Major concerns cited included workflow delays due to AI use, additional steps required such as sending images to a server, and unstable performance

The findings prompted the researchers to conclude that AI is likely to be implemented and used in the real world differently than in clinical trials. Radiologists should be included in AI algorithm development to provide insights into workflow where the tools will be used.

The Takeaway

The new study is unique in that – rather than focusing on AI algorithm performance – it concentrated on the experiences of radiologists using the software and how they changed following implementation. Such studies can be illuminating as AI developers seek broader clinical use of their tools. 

Creating a Cancer Screening Giant

A few days after shocking the AI and imaging center industries with its acquisitions of Aidence and Quantib, RadNet’s Friday investor briefing revealed a far more ambitious AI-enabled cancer screening strategy than many might have imagined.

Expanding to Colon Cancer – RadNet will complete its AI screening platform by developing a homegrown colon cancer detection system, estimating that its four AI-based cancer detection solutions (breast, prostate, lung, colon) could screen for 70% of cancers that are imaging-detectable at early stages.

Population Detection – Once its AI platform is complete, RadNet plans to launch a strategy to expand cancer screening’s role in population health, while making prostate, lung, and colon cancer screening as mainstream as breast cancer screening.

Becoming an AI Vendor – RadNet revealed plans to launch an externally-focused AI business that will lead with its multi-cancer AI screening platform, but will also create opportunities for RadNet’s eRAD PACS/RIS software. There are plenty of players in the AI-based cancer detection arena, but RadNet’s unique multi-cancer platform, significant funding, and training data advantage would make it a formidable competitor.

Geographic Expansion – RadNet will leverage Aidence and Quantib’s European presence to expand its software business internationally, as well as into parts of the US where RadNet doesn’t own imaging centers (RadNet has centers in just 7 states).

Imaging Center Upsides – RadNet’s cancer screening AI strategy will of course benefit its core imaging center business. In addition to improving operational efficiency and driving more cancer screening volumes, RadNet believes that the unique benefits of its AI platform will drive more hospital system joint ventures.

AI Financials – The briefing also provided rare insights into AI vendor finances, revealing that DeepHealth has been running at a $4M-$5M annual loss and adding Aidence / Quantib might expand that loss to $10M- $12M (seems OK given RadNet’s $215M EBITDA). RadNet hopes its AI division will become cash flow neutral within the next few years as revenue from outside companies ramp up.

The Takeaway

RadNet has very big ambitions to become a global cancer screening leader and significantly expand cancer screening’s role in society. Changing society doesn’t come fast or easy, but a goal like that reveals how much emphasis RadNet is going to place on developing and distributing its AI cancer screening platform going forward.

RadNet’s Big AI Play

Imaging center giant RadNet shocked the AI world this week, acquiring Dutch startups Aidence and Quantib to support its AI-enabled cancer screening strategy.

Acquisition Details – RadNet acquired Aidence for $40M-$50M and Quantib for $45M, positioning them alongside DeepHealth within its new AI division. Aidence’s Veye Lung Nodules solution (CT lung nodule detection) is used across seven European countries and has been submitted for FDA 510(k) clearance, while Quantib’s prostate and brain MRI solutions have CE and FDA clearance and are used in 20 countries worldwide.

RadNet’s Cancer Screening Strategy – RadNet sees a huge future for cancer screening and believes Aidence (lung cancer) and Quantib (prostate cancer) will combine with DeepHealth (breast cancer) to make it a population health screening leader. 

RadNet’s AI Screening History – Even if these acquisitions weren’t expected, they aren’t out of character for RadNet, which created its mammography AI portfolio through a series of 2019-2020 acquisitions (DeepHealth, Nulogix) and equity investments (WhiteRabbit.ai). Plus, acquisitions have been a core part of RadNet’s imaging center strategy since before we were even talking about AI.

Unanswered Questions – It’s still unclear whether RadNet will take advantage of Aidence / Quantib’s European presence to expand internationally or if RadNet will start selling its AI portfolio to other hospitals and imaging center chains.

Another Consolidation Milestone – All those forecasts of imaging AI market consolidation seem to be quickly coming true in 2022, following MaxQ’s pivot out of imaging and RadNet’s Aidence / Quantib acquisitions. It’s also becoming clearer what type of returns AI startups and VCs are willing to accept, as Aidance and Quantib sold for about 3.5-times and 5.5-times their respective venture funding ($14M & $8M) and Nanox acquired Zebra-Med for 1.7 to 3.5-times its VC funding ($57.4M).

The Takeaway

It seems that RadNet will leverage its newly-expanded AI portfolio to become the US’ premier cancer screening company. That would be a huge accomplishment if cancer screening volumes grow as RadNet is forecasting. However, RadNet’s combination of imaging AI expertise, technology, funding, and training data could allow it to have an even bigger impact beyond the walls of its imaging centers.

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