Author: Virginia Hunt

Cancer Survival Rates Rise as AI’s Impact Looms

Posted on by Virginia Hunt

More people are surviving cancer in the U.S. than ever before, even as the number of new U.S. cancer cases is expected to increase 19% by 2050. The AACR’s 2026 Cancer Progress Report showed rising cancer survival rates – especially for breast and lung cancer – and new technologies like AI could drive survival even higher.

The AACR report revealed big improvements in treatment and clinical outcomes…

  • The overall five-year survival rate for distant-stage cancer is more than double what it was three decades ago (17% to 36%). 
  • Since July 2025, the FDA approved 11 new anticancer therapies and additional uses for five existing interventions.

While that progress is coming fast, it has stalled in some areas… 

  • The pancreatic cancer survival rate remains low at 14%, compared with 92% for breast cancer and 98% for prostate cancer.
  • Disparities persist: Black men and American Indian/Alaska Native women had the highest cancer incidence rates from 2019 to 2023.
  • Across the same period, lung cancer rates were 37% higher in rural versus metropolitan areas.

Breast and lung cancer rank second and third for new diagnoses in the U.S., but advances in imaging-based screening for these cancers are accelerating… 

  • The U.S. breast cancer mortality rate declined by 44% from 1989 to 2024.
  • Breast cancer death rates have been decreasing by 1.2% per year.
  • Efforts to promote earlier detection are occurring, such as the USPSTF’s lowering of the recommended mammography screening age to 40.
  • Declines in lung cancer mortality accounted for the largest share of cancer deaths averted from 1975 to 2020, partly because of tobacco-control programs. 

But screening continues to be an essential tool to drive cancer mortality down even more, and AI could become a handy helper.

  • The MASAI trial found that AI-supported screening was associated with a 12% lower rate of interval cancers.
  • AI-assisted mammography detected early-stage breast cancer with greater sensitivity than standard screening without sacrificing specificity.
  • The report cited two recently cleared AI tools that can help with early detection: RevealDx’s RevealAI-Lung, which reportedly reduced false positives by 18%, and Median Technologies’ eyonis LCS, which showed 93% sensitivity in tests.

The tools could also help radiologists cope with the ongoing workforce shortage by stepping in as second readers or prioritizing high-risk cases. 

  • AI assistance could decrease reading workload by 44%, per the AACR report.

The Takeaway 

The AACR’s report shows encouraging progress in the war on cancer. In the future, AI advances could help radiologists continue to improve screening for lung and breast cancer patients, with some promising early evidence.

One Size Doesn’t Fit All for Asian American Cancer Risk

Posted on by Virginia Hunt

Nearly 1 in 8 women in the U.S. will be diagnosed with breast cancer, but those odds aren’t distributed equally across women of different racial backgrounds. And broad ethnic categories like “Asian American” may be masking big differences in breast cancer risk that could help inform better screening practices.

  • Breast cancer is the most commonly diagnosed cancer among women in every Asian American or Native Hawaiian/Pacific Islander (AA/NHPI) ethnic group.
  • But cancer incidence rates vary widely across groups bundled together under one ethnic or racial classification, so the one-size-fits-all approach to determining risk isn’t working.

New data show meaningful differences. In a study published in CANCER, researchers from the American Cancer Society analyzed detailed data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results program from 2000 to 2022…

  • Native Hawaiian women had breast cancer rates of 140 per 100k, 27% higher than white women.
  • Total cancer incidence rates varied twofold among groups who were labeled under the same AA/NHPI term.
  • For example, Native Hawaiian women had breast cancer rates 57% higher than the combined rate for AA/NHPI communities.

Early intervention is crucial as breast cancer rates continue to rise and screening uptake remains low in Asian women…

  • Breast cancer incidence is increasing annually, from 1% in Native Hawaiian and Filipino women to between 3% and 5% in Guamanian/Chamorro, Chinese, Vietnamese, and Korean women.
  • From 2015 to 2018, adherence rates for timely breast screening in women ≥45 years varied from 55% among Asian Indian women to 69% among Filipino women.

“You can’t fix a problem you don’t know is there.” 

  • As risk-based screening programs for breast cancer become more widely adopted, accurate statistics are increasingly important.
  • Breaking out data for Asian women could also improve targeted interventions for other cancers with wide risk ranges, including lung, stomach, and colorectal cancers.

Clearer data could help inform targeted interventions that aim to understand how structural barriers to care differ.

  • For example, NHPI women have a higher likelihood of being uninsured (12%) compared to Korean women (3%) in the U.S. 
  • Thus, study authors emphasize that just as a generic approach to risk determination isn’t cutting it, a one-size-fits-all approach to interventions won’t either.

The Takeaway

Risk awareness is increasingly driving mammography screening in the U.S., but grouping together women across different AA/NHPI ethnicities buries important differences that could help improve screening and early detection.

Could MRI Move the Needle in Prostate Cancer Workup?

Posted on by Virginia Hunt

Traditional systematic biopsy can miss clinically significant prostate cancers and often causes discomfort for patients along the way. While many countries have added MRI to prostate cancer workup protocols to determine which patients really need the needle, pre-biopsy MRI is used in only about one-third of U.S. prostate cancer workups – why?

More organized prostate cancer screening programs are popping up across the world. But a big challenge remains: deciding which patients with elevated PSA tests should undergo biopsy, and which ones can avoid or defer biopsy. That’s where MRI comes in…

  • ​​Australia, Canada, the U.K., and much of Europe have all adopted pre-biopsy MRI scans as the standard of care.
  • Pre-biopsy MRI scans are noninvasive and much more sensitive than traditional systematic biopsies, which typically obtain 10-12 cores to find lesions (93% vs. 50%).
  • The pace of MRI adoption for prostate cancer workup reflects ongoing disparities, with Black patients, people living outside cities, and Medicaid-eligible populations less likely to have access.

So, what’s the holdup in the U.S.? A new STAT article broke it down, finding:

  • Many U.S. urologists haven’t been trained in using MRI findings and/or performing MRI-targeted biopsy.
  • MRI access is still an issue across the country, especially in rural areas.

But something else may factor in: money. 

  • Biopsies can often be done in-house, so each procedure could mean up to $1.5k in reimbursement. 
  • Biopsies can detect low-grade cancers that might never become clinically significant, potentially leading to additional surveillance and repeat biopsies, which also generate revenue. 
  • Greater MRI use could reduce biopsy-related revenue.

Still, some organizations say yes to pre-biopsy scans, including the National Comprehensive Cancer Network, the American Urological Association, and the American Society of Clinical Oncology (albeit conditionally for the latter two).

  • Plus, a 2020 paper won over insurance companies to cover prostate MRI — but not all clinicians know that.
  • MRI scans have also proved helpful in other areas, like staging prostate cancer.

What could move the needle?

  • Training, ideally in urology residency, to overcome the knowledge gap early.
  • Education aimed at urologists and patients about reimbursement options and clinical benefits.
  • Improved access to high-quality MRI across the U.S.
  • Unified, implementation-focused programs like the one trialed in the Czech Republic, which led to a 10-percentage-point increase in pre-biopsy MRI utilization.

The Takeaway

The STAT article shows the U.S. is lagging far behind other countries in using MRI to diagnose and manage prostate cancer with more precision. Even though some major medical organizations are on board, broader implementation of MRI for patient workup requires overcoming limited training, barriers to technology access, and financial incentives that may favor biopsy.

Gaps in Global Cancer Burden Widen

Posted on by Virginia Hunt

About 20.6M people worldwide were diagnosed with cancer in 2024, a nearly 7% increase from 2020, WHO estimates. The number is sobering, and while the organization’s Global Status Report on Cancer 2026 revealed progress is being made, it isn’t being made equally.

The global cancer burden remains high.

  • Cancer led to nearly 17% of all global deaths in 2021 and was estimated to be the leading cause of premature deaths in 41 countries. 
  • As of 2024, breast cancer made up 25% of diagnoses in women. Lung cancer led male diagnoses, making up 16% of cancer incidence. 
  • Much of the burden is falling on younger populations: Nearly half of the 9.7M cancer-related deaths in 2024 were among people aged 30 to 69. 

WHO’s initial 2020 report set priorities to improve care — now it’s time for a temperature check. Some things have gotten better:

  • Global tobacco use decreased by 27% from 2010 to 2025.
  • HPV vaccination programs in 85% of countries have reduced infection-related cancers by 22%.

But it’s not all good news. Insufficient progress has been made in…

  • Radiotherapy access, with no radiation facilities at all in 23 low- and middle-income countries (LMICs).
  • Diagnostics, with 47% of populations lacking access to basic diagnostic services.

Breast cancer statistics bear out these disparities.

  • 28% of LMICs have an early diagnosis rate >60% versus 91% of high-income countries (HICs).
  • Early diagnosis = better survival odds. Many HICs had 5-year survival rates 4x higher than some sub-Saharan African countries, where the average 5-year survival rate was 39%.

The findings may sound familiar. Several U.S. studies have linked socioeconomic disparities to decreased screening rates – WHO’s report shows this distressing trend on a global scale. 

Still, WHO offers recommendations to mitigate the unequal burden of cancer. They outline seven specific shifts in capabilities, protections, and priorities that can be made by governments, clinicians, and civilians alike. They include: 

  • Embedding cancer control in universal health coverage.
  • Strengthening health system capacity.
  • Enhancing social protections.
  • Including individuals with lived experience of cancer in decision-making.
  • Promoting transparent data.
  • Aligning research with the needs of LMICs.
  • Unifying the global cancer agenda. 

The Takeaway

While WHO’s 2026 report on global cancer shows the world has made headway in battling the cancer burden, huge disparities in access to screening and treatment make it hard to celebrate just yet. Low- and middle-income countries continue to face decreased treatment access and survival rates, especially in breast cancer.

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