Author: Brian Casey

Health Inequity & Breast Cancer

Posted on by Brian Casey

The last several years have seen growing awareness of how structural inequities can impact individual health outcomes. Two powerful new JAMA Network Open studies reinforced what we know about structural inequity, particularly as it relates to breast cancer. 

In the first study on April 19 addressing racial differences in breast cancer mortality, researchers looked at over 415k women from 2011 to 2020, finding:

  • Black women between 40 and 49 years old had the highest breast cancer mortality rates per 100,000 person years, at 27 deaths. This compares to 15 deaths for White women, and 11 deaths for other ethnicities.
  • If breast screening were tailored based on risk at age 50, Black women should start screening eight years earlier than White women, at 42 years of age versus 51. 
  • Biennial mammography screening of Black women starting at age 40 would reduce the gap in breast cancer mortality compared to White women by 57%. 

In the second study on April 21, researchers drilled even deeper into structural inequity, focusing on breast cancer outcomes in disadvantaged neighborhoods in a large, racially diverse region in southern Florida that’s home to 6.2M people. 

In all, their study covered 5,027 women with breast cancer, and they categorized neighborhoods into three levels based on socioeconomic status. Findings included:

  • Patients living in the second most disadvantaged neighborhoods were 36% more likely to die of breast cancer (HR=1.36).  
  • Women living in the most disadvantaged neighborhoods were 77% more likely to die (HR=1.77).

The researchers pointed out that their results went beyond merely linking race to health outcomes, as they adjusted for race and ethnicity “as a proxy for structural racism.” They suggested that there could be “unaccounted,” biologic mechanisms related to neighborhood disadvantage that lead to shorter breast cancer survival. The findings echo other studies that have linked patient location to access to imaging.

The Takeaway

Over the past several decades, breast cancer’s dropping mortality rate has been a health policy success story. But the new studies indicate that progress has been uneven, and more attention is needed to ensure that the benefits of improved breast cancer diagnosis and treatment are distributed more equitably.

Headlines from HIMSS 2023

Posted on by Brian Casey

CHICAGO – It does indeed feel like 2019 again at HIMSS 2023, which opened this week in the Windy City. Major stories at the show include generative AI for medical use, consumer cloud players planting their flags in healthcare, and the ongoing need for healthcare IT to help with rising medical procedure volume and growing burnout among healthcare professionals.

But an underlying subtext of this week’s show is that the disruptions and travel restrictions of the COVID-19 pandemic are behind us. At long last the HIMSS show has returned to a sense of normalcy. 

On-site attendance at HIMSS 2022 in Orlando was around 29k, down sharply from the 43k at HIMSS 2019. Early midweek figures from HIMSS 2023 place attendance at 35k; this sounds about right based on the crowded hallways, presentation rooms, and technical exhibits at McCormick Place (and especially the line at Starbucks in the Grand Concourse). 

What are other trends at HIMSS 2023? They include: 

  • Generative AI spreading throughout healthcare. Radiology was one of the first medical specialties to explore the potential of large language models like ChatGPT, but healthcare IT is getting into the act as well. At HIMSS, vendors are inking partnerships to put ChatGPT to work for functions like clinical decision support.
  • Cloud storage providers are in healthcare to stay. After years of dabbling, the large cloud players – Amazon, Google, and Microsoft – appear to be making a major play in cloud-based healthcare, signing partnerships with IT and radiology OEMs.
  • Healthcare IT helping providers. The conversations at HIMSS 2023 are focusing on leveraging technology to help providers cope with rising procedure volume and burned-out staff. 
  • Pathology is finally ready to go digital. The technological challenges to digitizing, managing, and archiving massive whole slide images appear to be solved. Now all that’s left is to convince pathologists to take the digital plunge.

The Takeaway

Prior to the pandemic, HIMSS was perhaps the fastest-growing healthcare conference, and this week in Chicago shows it’s back. The crowded halls are a welcome sign not only for healthcare IT, but also for other medical meetings on the calendar.  

Check out videos from HIMSS 2023 on our LinkedIn page and YouTube channel. And keep an eye out for the editorial teams for Imaging Wire and our sister publications Cardiac Wire and Digital Health Wire in McCormick Place – we’d love to say hello!

Salary Data Reveal Medicine’s Golden Cage

Posted on by Brian Casey

Are you a glass-half-full or a glass-half-empty kind of person? Either way, there’s lots to unpack in the latest data on physician salaries, this time from Medscape. 

Medscape’s survey of over 10k US physicians across over 29 medical specialties found that overall physician salaries have grown 18% over the last five years, to $352k, while specialists made an average of $382k. 

As with last year, radiologists landed in the top 10 of highest-compensated specialists, a finding that’s in line with previous salary surveys, such as from Doximity. Medscape found that radiologists had an average annual salary of $483k in 2023, compared to $437k in 2022. Radiologists had an average annual salary of $504k in the Doximity data. 

Other nuggets from the Medscape survey:

  • “Stagnant” reimbursement relative to rising practice costs has cut into physician income. 
  • The gender gap is narrowing. Male primary care doctors in 2023 earn 19% more than females, compared to about 25% previously.
  • Male specialist physicians earn 27% more than females, down from 31% last year and 33% the year before that.
  • Only 19% of radiologists are women – one of the lowest rates of female participation among medical specialties. 
  • 58% of radiologists feel they are fairly paid.
  • Radiologists report working an average of 49.6 hours a week.
  • 90% of radiologists say they would choose their specialty again, ranking #10.

The Takeaway

On the positive side, physician salaries continue to rise, and medicine is making encouraging progress in narrowing the gender gap. Radiologists seem to be well-compensated and relatively happy, but the specialty has more to do to attract women.

Underlying the raw data is a disturbing undercurrent of physician dissatisfaction, with many feeling as though medicine is a golden cage. In the free-response portion of the survey, doctors described themselves as caught between falling reimbursement and rising costs, with overwork also leading to burnout. 

The Medscape survey shows that addressing physician burnout must become a priority for the US healthcare system, and it can’t be solved merely by boosting salaries. Increasing the number of residency slots is a good first step (see below).

Cardiac Imaging in 2040

Posted on by Brian Casey

What will cardiac imaging look like in 2040? It will be more automated and preventive, and CT will continue to play a major – and growing – role.

That’s according to an April 11 article in Radiology in which Dr. David Bluemke and Dr. João Lima look into the future and offer a top 10 list of major developments in cardiovascular imaging in 2040.

Cardiovascular disease carries a massive medical burden, with over 800,000 myocardial infarctions occurring annually in the US alone. By 2030 almost one-third of deaths worldwide are expected to be due to cardiovascular disease.

Multiple different imaging modalities are adept at identifying both ischemic and nonischemic heart disease, but CT has risen to the top for ischemic imaging, making “quantum” advances in the last decade thanks to its growing prowess in the coronary arteries.

CT’s advances have been so great that the modality occupies seven of the top 10 spots on Bluemke and Lima’s list. In brief, they see: 

  • Coronary CTA becoming totally automated, a development that will no doubt benefit AI developers like HeartFlow (see below).
  • CCTA becoming a preventive tool rather than a gatekeeper to interventional cardiology (also hinted at in a recent study from Denmark). For example, CCTA will be used to track the effectiveness of statin therapy
  • Photon-counting CT flexing its muscles for coronary artery evaluation and routine plaque characterization and quantification
  • Next-generation cardiac CT becoming more like MRI
  • Next-generation cardiac MRI becoming more like CT
Table of Top 10 Cardiovascular Imaging Developments by 2040

They also see a major growing role for software-assisted cardiac CT with AI and other tools. Software-based automation has simplified the “postprocessing nightmares” once common with coronary CT, making it “wonderfully ordinary” to perform. 

The Takeaway

Bluemke and Lima offer a fascinating glimpse of cardiac imaging’s future. But one area they don’t touch on is whether CT’s rising prominence means radiologists will start taking back turf in heart imaging once ceded to cardiologists. Heart specialists haven’t taken over cardiac CT in the same way that they monopolized echocardiography and nuclear cardiology. Could we be seeing a renaissance of radiology in the heart?

Ultrasound Spots Breech Pregnancies

Posted on by Brian Casey

Performing routine third-trimester ultrasound scans on pregnant women could help identify breech pregnancies, giving women the opportunity to consider alternative birth options. UK researchers in PLOS Medicine said the impact was found with both conventional and POCUS ultrasound scanners. 

While the incidence of breech presentation at full term is only 3-4%, when breech births do occur they can result in higher morbidity and mortality for both babies and mothers. 

In the UK, third-trimester ultrasound scans aren’t routinely performed for low-risk women, missing a chance to give them other options like Cesarean birth.

  • Therefore, researchers investigated the effectiveness and impact of these scans at two hospitals, one that used conventional ultrasound scanners and the other employing POCUS units (GE HealthCare’s Vscan Air).
  • At the POCUS facility, scans were typically performed by trained midwives. Women were scanned between 2016 to 2021 at both hospitals.

Performing routine ultrasound scans at 36 weeks reduced the incidence of undiagnosed breech presentation by 71% at the hospital using conventional ultrasound and 69% at the POCUS hospital.

  • The rate of undiagnosed breech presentation dropped from 14.2% to 2.8% with conventional ultrasound and from 16.2% to 3.5% with POCUS.
  • The scans also had an impact on babies’ health. Infants born at either facility had less likelihood of a lower Apgar score (<7) five minutes after birth, and babies were less likely to be sent to the neonatal care unit.

The researchers believe their findings suggest a revision of the UK’s clinical guidelines, which don’t currently call for routine third-trimester ultrasound scans for low-risk women. With respect to POCUS, they said their research was the first to investigate the technology for diagnosing fetal presentation, and their findings support wider use of POCUS in areas where conventional ultrasound isn’t available. 

The Takeaway

What’s really exciting about this study are the findings about POCUS. Maternal-fetal complications are a huge problem in developing countries and places with less access to imaging technology. POCUS scanners could be used by trained personnel like midwives – perhaps with AI assistance –  to identify problems before birth.

Radiology Puts ChatGPT to Work

Posted on by Brian Casey

ChatGPT has taken the world by storm since the AI technology was first introduced in November 2022. In medicine, radiology is taking the lead in putting ChatGPT to work to address the specialty’s many efficiency and workflow challenges. 

Both ChatGPT and its newest iteration, GPT-4, are forms of AI known as large language models – essentially neural networks that are trained on massive volumes of unlabeled text and are able to learn on their own how to predict the structure and syntax of human language. 

A flood of papers have appeared in just the last week or so investigating ChatGPT’s potential:

  • ChatGPT could be used to improve patient engagement with radiology providers, such as by creating layperson reports that are more understandable, or by answering patient questions in a chatbot function, says an American Journal of Roentgenology article.
  • ChatGPT offered up accurate information about breast cancer prevention and screening to patients in a study in Radiology. But ChatGPT also gave some inappropriate and inconsistent recommendations – perhaps no surprise given that many experts themselves often disagree on breast screening guidelines.
  • ChatGPT was able to produce a report on a PET/CT scan of a patient – including technical terms like SUVmax and TNM stage – without special training, found researchers writing in Journal of Nuclear Medicine.
  • GPT-4 translated free-text radiology reports into structured reports that better lend themselves to standardization and data extraction for research in another paper published in Radiology. Best of all, the service cost 10 cents a report.

Where is all this headed? A review article on AI in medicine in New England Journal of Medicine gave the opinion – often stated in radiology – that AI has the potential to take over mundane tasks and give health professionals more time for human-to-human interactions. 

They compared the arrival of ChatGPT to the onset of digital imaging in radiology in the 1990s, and offered a tantalizing future in which chatbots like ChatGPT and GPT-4 replace outdated technologies like x-ray file rooms and lost images – remember those?

The Takeaway

Radiology’s embrace of ChatGPT and GPT-4 is heartening given the specialty’s initial skeptical response to AI in years past. As the most technologically advanced medical specialty, it’s only fitting that radiology takes the lead in putting this transformative technology to work – as it did with digital imaging.

Software Closes Radiology Reporting Loop

Posted on by Brian Casey

In the never-ending quest to get referring physicians to follow radiologist recommendations for follow-up imaging, Massachusetts researchers in JAMA Network Open offer an IT-based solution: Structured reporting software that was found to triple the number of radiology reports judged to be complete. 

A recent study found that 65% of radiologist recommendations for follow-up imaging aren’t followed by referring physicians. Authors of that study found that recommendations that were strongly worded and communicated directly to referring doctors had higher uptake. 

But what if radiologists don’t follow this advice? In the new paper, researchers from Brigham and Women’s Hospital and Harvard Medical School offer a more structured solution thanks to software developed as part of their Addressing Radiologist Recommendations Collaboratively project. 

The ARCC software is a closed-loop communication system that’s designed to channel radiologist recommendations into a structured format that’s clearly understood, while also tracking whether they were accepted and fulfilled. The ARCC tool runs separately from the radiologist’s dictation software, so while it asks them to include a standardized recommendation sequence in their report, it leaves the specific free-text language up to them. 

Under the ARCC criteria, the main factors that make up a complete follow-up recommendation are:

  • Reason for imaging study
  • Timeframe when study should be completed
  • Imaging modality to be used

The researchers implemented the ARCC software in October 2019 in thoracic imaging, and rolled it out to other departments through December 2020. Use of the software was “strongly encouraged but voluntary.” 

In testing the ARCC software’s effectiveness, the researchers found that the number of follow-up recommendations considered to be complete – with all three key elements – rose from 14% to 46%. Even so, one-third of reports filed with ARCC “still contained ambiguous language” in the free-text section – indicating that old habits are hard to break.

The Takeaway

Radiologists may hate it when their recommendations for follow-up imaging are ignored, but referring physicians are also frustrated with free-text radiology reports that are wishy-washy and contain vague impressions. The ARCC software could bridge the gap by steering radiologists toward recommendations that are more concrete and specific – and more likely to be followed.

Is CCTA Set for Cardiac Screening?

Posted on by Brian Casey

A new study out of Denmark suggests that coronary CTA could be headed for population-based screening for heart disease. Researchers found that CCTA was remarkably effective in identifying individuals without symptoms who were more likely to experience heart attacks in years to come.

CCTA has proven so effective for cardiac imaging that it’s become a first-line test for stable chest pain, usually for those with symptoms. But researchers have debated whether CCTA’s value could be extended to asymptomatic individuals – which could set the stage for broad-based heart disease screening programs.

To investigate CCTA’s potential in the asymptomatic, researchers in Denmark scanned 9,533 individuals 40 years and older as part of the Copenhagen General Population Study, reporting their results in Annals of Internal Medicine. CCTA scans were conducted with Canon Medical’s 320-detector-row Aquilion One Vision scanner. 

Atherosclerosis was characterized as either obstructive (a luminal stenosis ≥ 50%), extensive (stenoses widely prevalent but not obstructive), or both. Researchers then tracked myocardial events over a median follow-up of 3.5 years. 

They found that 46% of study subjects had evidence of subclinical coronary atherosclerosis, with the type of atherosclerosis impacting risk of myocardial infarction: 

  • Extensive atherosclerosis had eight times higher risk 
  • Obstructive atherosclerosis had nine times higher risk
  • Both extensive and obstructive disease had 12 times higher risk

What’s more, researchers found that 10% of their study population had obstructive disease – which is just 10 percentage points under the 60% atherosclerosis threshold at which therapeutic intervention should be considered for asymptomatic people. 

Participants in the CGPS study did not receive treatment as part of the study, but the researchers have a follow-up study underway – DANE-HEART – in which asymptomatic people will get CCTA scans and some will be directed to preventive treatment if they meet clinical guidelines.

The Takeaway

This study demonstrates not only the widespread incidence of subclinical coronary atherosclerosis, but also CCTA’s ability to detect CAD before symptoms appear. Preventive treatment initiated and directed by CT findings could have a major impact on heart disease morbidity and mortality.

Given CCTA’s prognostic ability and the heavy burden of heart disease on society (more women die of heart disease than breast cancer, for example), how long before calls emerge to add CT-based heart screening to the arsenal of population-based screening programs? DANE-HEART may offer a clue.

Radiology Bucks Doctor Salary Decline

Posted on by Brian Casey

The latest news on physician salaries is out, and it’s not pretty. A new Doximity survey found that average physician pay declined 2.4% last year, compared to an increase of 3.8% in 2021. The drop was exacerbated by high inflation rates that took a bite out of physician salaries. 

The Doximity report paints a picture of physicians beset by rising burnout, shortages, and a persistent gender pay gap. Doctors across multiple specialties report feeling more stressed even as wage growth has stalled.

To compile the 2022 data, Doximity got responses from 31,000 US physicians. There was a wide range of average annual compensation across medical specialties, with radiology landing at number 10 on the top 20 list, while nuclear medicine occupied the 20th spot:

  • Radiation oncology: $547k vs. $544k in 2021
  • Radiology: $504k vs. $495k 
  • Nuclear medicine: $392k vs. $399k

In other findings of the report:

  • Male physicians made $110,000 more than women doctors. At a gap of 26%, this is actually an improvement compared to 28% in 2021.
  • Men physicians over their career make over $2 million more than women.
  • Nuclear medicine had the smallest pay gap ($394k vs. $382k)
  • The pay gap could contribute to higher burnout rates, with 92% of women reporting overwork compared to 83% of men. 
  • Two-thirds of physicians are considering an employment change due to overwork. 

Ironically, Doximity cited results of a recent survey in which 71% of physicians said they would accept lower compensation for better work-life balance. 

The Takeaway

The news about salaries could be a gut punch to many physicians, who are already dealing with epidemic levels of burnout. Radiology salaries bucked the trend by rising 1.6%, which could explain its popularity among medical students over the last three years. 

The question remains, is the money worth it? Rising imaging volumes have been tied to burnout in radiology, and the Doximity report indicates that some physicians are willing to forgo money for better quality of life.

Moral Distress in Radiology

Posted on by Brian Casey

The rising volume of medical imaging studies isn’t just a data point. It’s causing moral distress among radiologists and is a major systemic cause of the specialty’s burnout epidemic. 

Radiology’s problem with burnout is no secret, with a recent analysis disclosing that 54% of all radiologists identify as burned out. Studies have found that a cause of burnout can be moral distress, defined within healthcare as when a clinician knows the right course of action for a patient, but is prevented from taking it due to systemic factors.

In a March 22 study in American Journal of Roentgenology, researchers describe findings from a survey of 93 radiologists on their feelings of moral distress in different clinical scenarios and the impact it had on their careers. In short:

  • 98% reported some degree of moral distress
  • 48% thought the COVID-19 pandemic influenced their moral distress
  • 28% considered leaving their jobs
  • 18% actually did leave a job

Several factors contribute to moral distress in radiology: 

  • Case volumes that are higher than can be read safely
  • Higher case volumes that prevent resident teaching
  • A lack of action and support among administration

These latter issues lead to burnout in specific ways, the authors wrote. Institutional constraints to providing high-quality care can prompt physicians to spend more time at work. Error rates can also grow during shifts with high study volumes or that last longer than 10 hours. And orders for unnecessary imaging exams can be seen as disregard for professional expertise. 

The Takeaway

This study rips the Band-Aid off the burnout problem in radiology, pointing out that inexorably rising imaging volumes rather than bad bosses or lazy colleagues are a root cause, one that’s been exacerbated by the COVID-19 pandemic.  

A further implication is that no amount of “self-care” – often prescribed as a solution for burnout – will cure the problem in the long run as long as radiologists will have ever-growing worklists to return to after their sabbaticals and motivational staff meetings. The researchers recommended “urgent action” to address the issue.

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